IgG4-related Lung Pseudotumor and Pleural Inflammation with Autoimmune Hepatitis

نویسندگان

  • Kazunori Nagashima
  • Itsuki Sano
  • Tomoe Kobayashi
  • Kazunori Eto
  • Kosuke Nagai
  • Ryusuke Ninomiya
  • Akira Suzuki
  • Yoshihiro Oohata
  • Kouhei Konishi
  • Tsuyoshi Nakano
  • Fumiyasu Yamamoto
چکیده

A 63-year-old man was admitted to our department following a secondary medical examination. Blood tests showed high levels of liver enzymes, IgG, IgG4, and antinuclear antibody. Computed tomography showed tumors in the bilateral lower lobes of the lungs and pleural thickening. After pleural and liver biopsy procedures, he was conclusively diagnosed with IgG4-related lung pseudotumor and pleural inflammation with autoimmune hepatitis. We started treatment with prednisolone 40 mg/day, and chest radiograph and blood tests showed signs of improvement. This was a rare case that suggested an association between IgG4-related disease and autoimmune hepatitis.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

IgG4 related disease in pancreas, bile duct and liver

IgG4-related disease is a unique systemic inflammatory condition characterized by pseudotumorous formation or swelling of affected organs and high-serum IgG4 concentrations. Further studies have demonstrated that IgG4-related disease can involve a variety of organs including the pancreas ( type 1 autoimmune pancreatitis) , bile duct ( IgG4-related sclerosing cholangitis), liver (IgG4-related he...

متن کامل

IgG4‐related disease in asbestos‐related pleural disease

A 67-year-old man with a history of asbestos exposure and rounded atelectasis complained of cough and swelling in the left submandibular region. Computed tomography showed an increase in size of the right lower lung lobe lesion, which was recognized as the pre-existing rounded atelectasis, as well as swelling of the pancreas and submandibular glands. Biopsy from a submandibular gland and the pu...

متن کامل

Isolated IgG4-related interstitial lung disease: unusual histological and radiological features of a pathologically proven case

IgG4-related lung disease is commonly associated with autoimmune pancreatitis. Recently, isolated IgG4-related interstitial lung disease (ILD) without other organ involvement has newly been reported in two cases with clinical features of nonspecific interstitial pneumonitis (NSIP).We report the first case of an isolated IgG4-related ILD in a 78-year-old man with dry cough and dyspnea, whose cli...

متن کامل

IgG4-related lung and pleural disease: a clinicopathologic study of 21 cases.

Immunoglobulin G4 (IgG4)-related disorders can occur in the respiratory system. However, the clinicopathologic characteristics have not been well clarified. In this study, we examined clinical and pathologic features of, and follow-up data on, IgG4-related lung and pleural lesions. The patients group consisted of 17 males and 4 females with an average age of 69 years (range: 42 to 76). Pulmonar...

متن کامل

A Case of Hypertrophic Pachymeningitis with Elevated Serum IgG4

Immunoglobulin G4 (IgG4)-related disease is a recently defined disease entity, characterized by high serum IgG4 concentration and comprised of a spectrum of systemic disorders, including Mikulicz’s disease; autoimmune pancreatitis; Riedel’s thyroiditis; sclerosing cholangitis; retroperitoneal fibrosis; tubulointerstitial nephritis; and lung lesions, such as hilar lymphadenopathy, pseudotumor an...

متن کامل

ذخیره در منابع من

ذخیره در منابع من قبلا به منابع من ذحیره شده

{@ msg_add @}


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره 57  شماره 

صفحات  -

تاریخ انتشار 2018